Clinical Stages of HIV Infection and Disease

Clinical Stage

Associated Condition

Performance Scale

1

1. Acute retroviral infection
2. Asymptomatic
3. Persistent generalised lymphadenopathy

Scale 1

Asymptomatic

Normal activity

2

1. Weight loss of more than 10% body weight
2. Minor mucocutaneous manifestations
3. Herpes zoster within the last 5 years
4. Recurrent upper respiratory infections

Scale 2

Symptomatic

Normal activity

3

1. Weight loss (same as above)
2. Unexplained chronic diarrhoea about 1 month
3. Unexplained prolonged fever
4. Oral candidiasis
5. Vulvo-vaginal candidiasis, chronic or poorly responsive to therapy
6. Oral hairy leukoplakia
7. Pulmonary tuberculosis
8. Severe bacterial infections (e.g. pneumonia)

Scale 3

Bedridden 50% of the day during the last month

4 (AIDS Defining Conditions)

1. HIV wasting syndrome
2. Pneumocystic carinnii pneumonia
3. Toxoplasmosis of the brain
4. Cryptosporidiosis with diarrhoea
5. Cryptosporidiosis, extrapulmonary
6. Cytomegalovirus
7. Herpes simplex infections
8. Progressive multifocal leuco-encephalopathy
9. Any disseminated endemic mycosis
10. Candidiasis of the oesophagus, trachea, bronchi or lungs
11. Disseminated Atypical mycobacteriosis
12. Non typhoidal salmonella septicaemia
13. Extrapulmonary tuberculosis
14. Lymphoma
15. Kaposi’s sarcoma
16. HIV encephalopathy